Anti-Syndecan 4/SDC4 Antibody Picoband® Fluoro488 Conjugated

Syndecan 4 is also known as SDC4. The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.

Cell Adhesion Proteins, Cytoskeleton/ECM, ECM Proteins, Neurogenesis, Neurology Process, Neuroscience, Plasma Membrane, Signal Transduction, Subcellular Markers, Tags & Cell Markers

1. Entrez Gene: SDC4 syndecan 4. 2. Woods A, Couchman JR (May 1998) . Syndecans: synergistic activators of cell adhesion. Trends Cell Biol. 8 (5) : 189–92.