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CREB-1 Monoclonal Antibody

Mouse Anti-CREB-1 Monoclonal Antibody

Product Specifications

Background

CREB1 (cAMP responsive element binding protein 1) encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of CREB1 results in several transcript variants encoding different isoforms.

Gene ID

1385

Accession Number

P16220

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant Protein

Clonality

Monoclonal

Tag

Cyclic AMP-responsive element-binding protein 1

Applications

WB, IF, ELISA

Purification Method

Protein G

Concentration

1 mg/ml

Molecular Weight

45kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous CREB-1 protein.

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IF 1:100-500; ELISA 1:1000-5000

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Mouse

Accession Number URL

http://www.uniprot.org/uniprot/P16220

Isotype

Mouse IgG1

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