CREB-1 Monoclonal Antibody
Mouse Anti-CREB-1 Monoclonal Antibody
Product Specifications
Background
CREB1 (cAMP responsive element binding protein 1) encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of CREB1 results in several transcript variants encoding different isoforms.
Gene ID
1385
Accession Number
P16220
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant Protein
Clonality
Monoclonal
Tag
Cyclic AMP-responsive element-binding protein 1
Applications
WB, IF, ELISA
Purification Method
Protein G
Concentration
1 mg/ml
Molecular Weight
45kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous CREB-1 protein.
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IF 1:100-500; ELISA 1:1000-5000
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Mouse
Accession Number URL
http://www.uniprot.org/uniprot/P16220
Isotype
Mouse IgG1
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