XRCC4 Monoclonal Antibody
Mouse Anti-XRCC4 Monoclonal Antibody
Product Specifications
Background
X-ray repair cross complementing 4 encoded by XRCC4 functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. X-ray repair cross complementing 4 plays a role in both non-homologous end joining and the completion of V (D) J recombination. Mutations in XRCC4 can cause short stature, microcephaly, and endocrine dysfunction (SSMED) . Alternative splicing generates several transcript variants.
Product Name Alternative
XRCC4; DNA repair protein XRCC4; X-ray repair cross-complementing protein 4
Gene ID
7518
Accession Number
Q13426
Reactivity
Human
Immunogen
Synthetic Peptide
Clonality
Monoclonal
Tag
DNA repair protein XRCC4
Applications
WB, IHC, IF, IP
Purification Method
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Molecular Weight
38kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous XRCC4 proteins.
Formulation
Liquid solution
Buffer pH
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:2000; IP 1:200; IF 1:200; IHC 1:50-300
Other Product Names
XRCC4; DNA repair protein XRCC4; X-ray repair cross-complementing protein 4
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Mouse
Accession Number URL
http://www.uniprot.org/uniprot/Q13426
Isotype
Mouse IgG1
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