XRCC4 Monoclonal Antibody

Mouse Anti-XRCC4 Monoclonal Antibody

Product Specifications

Background

X-ray repair cross complementing 4 encoded by XRCC4 functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. X-ray repair cross complementing 4 plays a role in both non-homologous end joining and the completion of V (D) J recombination. Mutations in XRCC4 can cause short stature, microcephaly, and endocrine dysfunction (SSMED) . Alternative splicing generates several transcript variants.

Product Name Alternative

XRCC4; DNA repair protein XRCC4; X-ray repair cross-complementing protein 4

Gene ID

7518

Accession Number

Q13426

Reactivity

Human

Immunogen

Synthetic Peptide

Clonality

Monoclonal

Tag

DNA repair protein XRCC4

Applications

WB, IHC, IF, IP

Purification Method

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Concentration

1 mg/ml

Molecular Weight

38kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous XRCC4 proteins.

Formulation

Liquid solution

Buffer pH

PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:2000; IP 1:200; IF 1:200; IHC 1:50-300