Aquaporin 4 Monoclonal Antibody

Mouse Anti-Aquaporin 4 Monoclonal Antibody

Product Specifications

Background

AQP4 encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. Aquaporin 4 is the predominant aquaporin found in brain and has an important role in brain water homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for AQP4. A recent study provided evidence for translational readthrough in AQP4 and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.

Product Name Alternative

AQP4; Aquaporin-4; AQP-4; Mercurial-insensitive water channel; MIWC; WCH4

Gene ID

361

Accession Number

P55087

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic Peptide

Clonality

Monoclonal

Tag

Aquaporin-4

Applications

WB, IHC, IF

Purification Method

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Concentration

1 mg/ml

Molecular Weight

48kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous Aquaporin 4 proteins.

Formulation

Liquid solution

Buffer pH

PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:1000; IF 1:100-200; IHC 1:50-300