DUB-IN-3
DUB-IN-3 (compound 22c) is a potent and selective inhibitor of the deubiquitinating enzyme USP8 with an IC50 value of 0.56 μM. DUB-IN-3 is promising for research of cancer, neurodegenerative diseases, inflammation, viral infection and cardiovascular disease[1].
Product Specifications
CAS Number
924296-17-3
UNSPSC
12352005
Hazard Statement
H228, H315, H319
Target
Deubiquitinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer; Infection; Inflammation/Immunology; Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/DUBs-IN-3.html
Concentration
10mM
Purity
99.00
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
C=CCO/N=C1C2=C(N=C(C#N)C(C#N)=N2)C3=CC=CC=C/13
Molecular Formula
C16H9N5O
Molecular Weight
287.28
Precautions
H228, H315, H319
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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