Anti-Legionella pneumophila serogroup 1 LPS Antibody

ELISA: use at 0.1-1.0ug/ml with LPS on the solid phase at 5ug/ml. <br><br>These are recommended concentrations. <br><br>End users should determine optimal concentrations for their applications.

This antibody recognizes LPS of L. pneumophila serogroup 1 (SG1). It does not react with serogroups 2-9, Legionella bozemanae, or Branhamella catarrharlis.

Legionella pneumophila are Gram- negative aerobic coccobacilli isolated from natural and artificial fresh water reservoirs. The outer membrane of L. pneumophila is comprised of a unique lipopolysaccharide (LPS) which is less endotoxic than enterobacterial LPS. Serogroups of L. pneumophila are classified based on O- antigen determinants of their cell wall side chains. L. pneumophila is pathogenic for humans, and it has no known soil or animal sources. It is responsible for more than 98% of the cases of Legionnaires' Disease, and about 95% of cases are due to serogroup 1. It has been isolated from numerous environmental sites as well as from human lung tissue, respiratory secretions, blood, and urine.