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EMAC10101d

EMAC10101d is a potent and selective toward hCA II inhibitor, with a Ki of 8.1 nM[1].

Product Specifications

CAS Number

[2561476-24-0]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Carbonic Anhydrase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/emac10101d.html

Purity

99.77

Solubility

DMSO : 62.5 mg/mL (ultrasonic)

Smiles

O=S(C1=CC=C(/N=C2SC=C(C3=CC=C(Cl)C=C3Cl)N\2CC)C=C1)(N)=O

Molecular Formula

C17H15Cl2N3O2S2

Molecular Weight

428.36

Precautions

H302, H315, H319, H335

References & Citations

[1]Rita Meleddu, et al. New Dihydrothiazole Benzensulfonamides: Looking for Selectivity toward Carbonic Anhydrase Isoforms I, II, IX, and XII. ACS Med Chem Lett. 2020 Feb 13;11 (5) :852-856.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

CA II

Available Sizes

Curated Selection

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