p-Cresyl sulfate (potassium)
Product Specifications
UNSPSC Description
p-Cresyl sulfate potassium is a uremic toxin that binds to a prototype protein. p-Cresyl sulfate potassium activates the JNK and p38 MAPK signaling pathways. p-Cresyl sulfate potassium has pro-inflammatory activity[1][2].
Target Antigen
Endogenous Metabolite; JNK; p38 MAPK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway;Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/p-Methylphenyl_potassium_sulfate.html
Purity
99.92
Solubility
DMSO : 125 mg/mL (ultrasonic;warming;heat to 60°C)|H2O : ≥ 100 mg/mL
Smiles
O=S(OC1=CC=C(C)C=C1)(O[K])=O
Molecular Weight
226.29
References & Citations
[1]Tanaka H, et al, Fukagawa M. p-Cresyl sulfate induces osteoblast dysfunction through activating JNK and p38 MAPK pathways. Bone. 2013 Oct;56(2):347-54.|[2]Koppe L, et al. p-Cresyl sulfate promotes insulin resistance associated with CKD. J Am Soc Nephrol. 2013 Jan;24(1):88-99.ACS Appl Bio Mater. 2024 Jun 5.|Cell Metab. 2024 Jun 18:S1550-4131(24)00189-X.|Colloids Surf B Biointerfaces. 2024 Aug 13:244:114164.|Cell Death Dis. 2023 Feb 2;14(2):78.|Phytomedicine. 2024 Oct 28:135:156174.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-111431A/p-Cresyl-sulfate-potassium-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-111431A/p-Cresyl-sulfate-potassium-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
91978-69-7
Available Sizes
Curated Selection
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