Perfluorohexyloctane

Perfluorohexyloctane (NOV03), a semifluorinated alkane, reduces tear film instability in Meibomian gland dysfunction and evaporative dry eye disease. Perfluorohexyloctane is a long-term tamponade agent. Perfluorohexyloctane increases tear film breakup time and lipid layer thickness[1].

Product Specifications

CAS Number

[133331-77-8]

Product Name Alternative

NOV03; SHR8058

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Concentration

10mM

Purity

99.05

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)CCCCCCCC

Molecular Formula

C14H17F13

Molecular Weight

432.26

Precautions

H302, H315, H319, H335

References & Citations

[1]Delicado-Miralles M, et al. Deciphering the Action of Perfluorohexyloctane Eye Drops to Reduce Ocular Discomfort and Pain. Front Med (Lausanne) . 2021 Oct 26;8:709712.|[2]Malchiodi-Albedi F, et al. Perfluorohexyloctane (F6H8) induces structural modifications and increases apoptosis in rat primary retinal cultures. J Biomed Mater Res B Appl Biomater. 2003 Apr 15;65 (1) :133-6.|[3]Zeana D, et al. Perfluorohexyloctane as a long-term vitreous tamponade in the experimental animal. Experimental perfluorohexyloctane substitution. Int Ophthalmol. 1999;23 (1) :17-24.