Mps-BAY1
Product Specifications
UNSPSC Description
Mps-BAY1 is an MPS1 inhibitor with anticancer activity. Mps-BAY1 inhibits cell proliferation and induces apoptosis by activating mitotic catastrophe in cancer cells, generating global aneuploidy and polyploidy. Mps-BAY1 can be used in the study of colorectal cancer and cervical cancer[1].
Target Antigen
Apoptosis; Mps1
Type
Reference compound
Related Pathways
Apoptosis;Cell Cycle/DNA Damage;Cytoskeleton
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mps-bay1.html
Smiles
N#CC1=C(NC2=NN3C=C(C4=CC=C(NC(CC5=CC=CC=C5)=O)C=C4)C=CC3=N2)C=CC=C1
Molecular Weight
444.49
References & Citations
[1]Jemaa, et al. "Characterization of novel MPS1 inhibitors with preclinical anticancer activity." Cell Death & Differentiation 20.11 (2013): 1532-1545.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-164501/Mps-BAY1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-164501/
Clinical Information
No Development Reported
CAS Number
1309593-24-5
Curated Selection
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