Cytosine
Cytosine is one of the four main bases found in DNA and RNA. Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging. Cytosine can be used in cancer research[1][2][3][4].
Product Specifications
CAS Number
71-30-7
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/6-Aminopyrimidin-2_1H_-one.html
Concentration
10mM
Purity
99.99
Solubility
DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1NC=CC(N)=N1
Molecular Formula
C4H5N3O
Molecular Weight
111.10
Precautions
H302, H315, H319, H335
References & Citations
[1]Maxam AM, et, al. A new method for sequencing DNA. Proc Natl Acad Sci U S A. 1977 Feb;74 (2) :560-4.|[2]Oh G, et, al. Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging. Nat Commun. 2018 Feb 13;9 (1) :644.|[3]Ngo TT, et al. Effects of cytosine modifications on DNA flexibility and nucleosome mechanical stability. Nat Commun. 2016 Feb 24;7:10813. |[4]Warnecke PM, et al. Cytosine methylation and human cancer. Curr Opin Oncol. 2000 Jan;12 (1) :68-73.
Shipping Conditions
Room Temperature
Storage Conditions
RT, protect from light
Scientific Category
Natural Products
Clinical Information
Phase 4
Isoform
Human Endogenous Metabolite; Microbial Metabolite
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