Cytosine

Cytosine is one of the four main bases found in DNA and RNA. Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging. Cytosine can be used in cancer research[1][2][3][4].

Product Specifications

CAS Number

[71-30-7]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/6-Aminopyrimidin-2_1H_-one.html

Concentration

10mM

Purity

99.99

Solubility

DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C1NC=CC(N)=N1

Molecular Formula

C4H5N3O

Molecular Weight

111.10

Precautions

H302, H315, H319, H335

References & Citations

[1]Maxam AM, et, al. A new method for sequencing DNA. Proc Natl Acad Sci U S A. 1977 Feb;74 (2) :560-4.|[2]Oh G, et, al. Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging. Nat Commun. 2018 Feb 13;9 (1) :644.|[3]Ngo TT, et al. Effects of cytosine modifications on DNA flexibility and nucleosome mechanical stability. Nat Commun. 2016 Feb 24;7:10813. |[4]Warnecke PM, et al. Cytosine methylation and human cancer. Curr Opin Oncol. 2000 Jan;12 (1) :68-73.