Rocepafant
Rocepafant (BN 50730) is a specific platelet activating factor (PAF) antagonist. Rocepafant can be used in rheumatoid arthritis and nervous system research[1].
Product Specifications
CAS Number
132579-32-9
Product Name Alternative
BN 50730; LAU-8080
UNSPSC
12352005
Target
Platelet-activating Factor Receptor (PAFR)
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/rocepafant.html
Smiles
S=C(N(C1)CCC2=C1SC3=C2C(C4=CC=CC=C4Cl)=NCC5=NN=C(C)N53)NC6=CC=C(OC)C=C6
Molecular Formula
C26H23ClN6OS2
Molecular Weight
535.08
References & Citations
[1]Silva CL, et al. Formation of a highly stable complex between BN 50730 [tetrahydro-4,7,8,10 methyl-1 (chloro-2 phenyl) -6 (methoxy-4 phenyl-carbamoyl) -9 pyrido [4',3'-4,5] thieno [3,2-f] triazolo-1,2,4 [4,3-a] diazepine-1,4] and the platelet-activating factor receptor in rabbit platelet membranes. Biochem Pharmacol. 1996 Jan 26;51 (2) :193-6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3
Available Sizes
Frequently Asked Questions
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