Human TWEAK Protein, Fc Tag (SPR verified)
Human TWEAK Protein, Fc Tag (TWK-H5263) is expressed from human 293 cells (HEK293) . It contains AA Ser 94 - His 249 (Accession # O43508-1) .
Product Specifications
Background
TWEAK (tumor necrosis factor-like weak inducer of apoptosis) is a member of the TNF superfamily that controls a multitude of cellular events including proliferation, migration, differentiation, apoptosis, angiogenesis, and inflammation. TWEAK exists in both membrane-bound and secreted forms, and can induce cell apoptosis via multiple pathways of cell death in a cell type-specific manner. It has also been found to promote the proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis.
Specifications
This protein carries a human IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 43.6 kDa. The protein migrates as 33 kDa and 48-53 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
O43508-1
Expression Region
Ser 94 - His 249
Host
HEK293
Target
TWEAK
Conjugation
Unconjugated
Tag
N-Fc
Source
Human
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
95%
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
43.6 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
100ug*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/TWK-H5263.pdf
Species
Human
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