Oleanolic acid 28-O-β-D-glucopyranoside
Oleanolic acid 28-O-β-D-glucopyranoside (β-D-Glucopyranosyl oleanolate) is an orally active pentacyclic triterpenoid compound. Oleanolic acid 28-O-β-D-glucopyranoside has anti-inflammatory effects. In ulcerative colitis models, Oleanolic acid 28-O-β-D-glucopyranoside can inhibit the inflammatory response, enhance the intestinal epithelial barrier function, and modulate the gut microbiota. Its mechanism of action is related to the PI3K-AKT and MAPK signaling pathways. Oleanolic acid 28-O-β-D-glucopyranoside can be used in the research of diseases such as colitis[1][2].
Product Specifications
CAS Number
14162-53-9
Product Name Alternative
β-D-Glucopyranosyl oleanolate
UNSPSC
12352005
Target
Akt; Claudin; COX; Interleukin Related; NO Synthase; p38 MAPK; PI3K
Type
Natural Products
Related Pathways
Cytoskeleton; Immunology/Inflammation; MAPK/ERK Pathway; PI3K/Akt/mTOR
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/oleanolic-acid-28-o-β-d-glucopyranoside.html
Purity
99.42
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C([C@](CC[C@]12C)(CCC3(C)C)[C@](C3)([H])C1=CC[C@@]4([H])[C@]2(CC[C@](C(C)5C)([H])[C@@]4(CC[C@@H]5O)C)C)O[C@@H]([C@@H]([C@H]6O)O)O[C@@H]([C@H]6O)CO
Molecular Formula
C36H58O8
Molecular Weight
618.84
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
COX-2; IL-6
Available Sizes
Frequently Asked Questions
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