Ac-AAVALLPAVLLALLAP-YVAD-CHO

Ac-AAVALLPAVLLALLAP-YVAD-CHO is a cell-permeable caspase-1 inhibitor that has antitumor activity[1].

Product Specifications

CAS Number

[201608-12-0]

UNSPSC

12352209

Target

Caspase

Type

Peptides

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ac-aavallpavllallap-yvad-cho.html

Solubility

10 mM in DMSO

Smiles

CC(N[C@@H](C)C(N[C@@H](C)C(N[C@@H](C(C)C)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N1[C@@H](CCC1)C(N[C@@H](C)C(N[C@@H](C(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N2[C@@H](CCC2)C(N[C@H](C(N[C@@H](C(C)C)C(N[C@@H](C)C(N[C@H](C=O)CC(O)=O)=O)=O)=O)CC3=CC=C(C=C3)O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C97H160N20O24

Molecular Weight

1990.43

References & Citations

[1]S Schlosser, et al. Inhibition of caspase-1 induces cell death in pancreatic carcinoma cells and potentially modulates expression levels of bcl-2 family proteins. FEBS Lett. 2001 Feb 23;491 (1-2) :104-8.