NH-bis-PEG2
NH-bis-PEG2 is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . NH-bis-PEG2 is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product Specifications
CAS Number
[54384-47-3]
UNSPSC
12352203
Hazard Statement
H315, H319
Target
ADC Linker; PROTAC Linkers
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nh-bis-peg2.html
Purity
97.0
Solubility
10 mM in DMSO
Smiles
OCCOCCNCCOCCO
Molecular Formula
C8H19NO4
Molecular Weight
193.24
Precautions
H315, H319
References & Citations
[1]Brown A, et al. PEG-lipid micelles enable cholesterol efflux in Niemann-Pick Type C1 disease-based lysosomal storage disorder. Sci Rep. 2016 Aug 30;6:31750.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Non-cleavable Linker; PEG Linkers
Available Sizes
Curated Selection
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