NH-bis-PEG2

NH-bis-PEG2 is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . NH-bis-PEG2 is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product Specifications

CAS Number

[54384-47-3]

UNSPSC

12352203

Hazard Statement

H315, H319

Target

ADC Linker; PROTAC Linkers

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related; PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/nh-bis-peg2.html

Purity

97.0

Solubility

10 mM in DMSO

Smiles

OCCOCCNCCOCCO

Molecular Formula

C8H19NO4

Molecular Weight

193.24

Precautions

H315, H319

References & Citations

[1]Brown A, et al. PEG-lipid micelles enable cholesterol efflux in Niemann-Pick Type C1 disease-based lysosomal storage disorder. Sci Rep. 2016 Aug 30;6:31750.