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NH-bis-PEG2

NH-bis-PEG2 is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . NH-bis-PEG2 is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product Specifications

CAS Number

[54384-47-3]

UNSPSC

12352203

Hazard Statement

H315, H319

Target

ADC Linker; PROTAC Linkers

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related; PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/nh-bis-peg2.html

Purity

97.0

Solubility

10 mM in DMSO

Smiles

OCCOCCNCCOCCO

Molecular Formula

C8H19NO4

Molecular Weight

193.24

Precautions

H315, H319

References & Citations

[1]Brown A, et al. PEG-lipid micelles enable cholesterol efflux in Niemann-Pick Type C1 disease-based lysosomal storage disorder. Sci Rep. 2016 Aug 30;6:31750.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-130328/NH-bis-PEG2-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-130328/NH-bis-PEG2-SDS-MedChemExpress.pdf

Scientific Category

ADC Related

Clinical Information

No Development Reported

Isoform

Non-cleavable Linker; PEG Linkers

Available Sizes

Curated Selection

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