Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

AKOS-22

AKOS-22 is a potent mitochondrial protein VDAC1 (voltage-dependent anion channel 1) inhibitor (Kd=15.4 μM) . AKOS-22 interacts with VDAC1 and inhibiting both VDAC1 oligomerization and apoptosis. AKOS-22 protects against mitochondrial dysfunction[1].

Product Specifications

CAS Number

878983-38-1

UNSPSC

12352005

Target

Mitochondrial Metabolism; VDAC

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/akos-22.html

Purity

99.23

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(C(N1CCC(NC2=CC=C(OC(F)(F)F)C=C2)CC1)C3)N(C4=CC=C(Cl)C=C4)C3=O

Molecular Formula

C22H21ClF3N3O3

Molecular Weight

467.87

References & Citations

[1]Ben-Hail D, et al. Novel Compounds Targeting the Mitochondrial Protein VDAC1 Inhibit Apoptosis and Protectagainst Mitochondrial Dysfunction. Biol Chem. 2016 Nov 25;291 (48) :24986-25003.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

PerCP Anti-Human/Mouse/Rat CD47 Antibody[MIAP410]
E-AB-F1016F-01 20 Tests

PerCP Anti-Human/Mouse/Rat CD47 Antibody[MIAP410]

Sign In for Pricing
View Details
PerCP Anti-Human/Mouse/Rat CD47 Antibody[MIAP410]
E-AB-F1016F-02 100 Tests

PerCP Anti-Human/Mouse/Rat CD47 Antibody[MIAP410]

Sign In for Pricing
View Details
PerCP Anti-Human/Mouse/Rat CD47 Antibody[MIAP410]
E-AB-F1016F-03 2x 100 Tests

PerCP Anti-Human/Mouse/Rat CD47 Antibody[MIAP410]

Sign In for Pricing
View Details
C12orf74 (NM_001037671) Human Over-expression Lysate
LY421977 100 µg

C12orf74 (NM_001037671) Human Over-expression Lysate

Sign In for Pricing
View Details
FAM119A (METTL21A) (NM_145280) Human Recombinant Protein
TP307629M 100 µg

FAM119A (METTL21A) (NM_145280) Human Recombinant Protein

Sign In for Pricing
View Details
Tissue Protein Lysate, Small intestine
CP565611 150 µg

Tissue Protein Lysate, Small intestine

Sign In for Pricing
View Details