Esomeprazole (potassium salt)

Esomeprazole potassium salt ((S) -Omeprazole potassium salt) is a potent and orally active proton pump inhibitor and reduces acid secretion through inhibition of the H+, K+-ATPase in gastric parietal cells. Esomeprazole potassium salt has the potential for symptomatic gastroesophageal reflux disease research[1][2][3].

Product Specifications

CAS Number

[161796-84-5]

Product Name Alternative

(S) -Omeprazole (potassium salt) ; (-) -Omeprazole (potassium salt)

UNSPSC

12352005

Hazard Statement

H302

Target

Bacterial; Proton Pump

Type

Reference compound

Related Pathways

Anti-infection; Membrane Transporter/Ion Channel

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer; Endocrinology; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/Esomeprazole-potassium-salt.html

Purity

98.18

Solubility

DMSO : 38.35 mg/mL (ultrasonic; warming)

Smiles

O=[S@](C1=NC2=CC=C(OC)C=C2[N-]1)CC3=NC=C(C)C(OC)=C3C.[K+]

Molecular Formula

C17H18KN3O3S

Molecular Weight

383.51

Precautions

H302

References & Citations

[1]Wayne Goh, et al. Use of proton pump inhibitors as adjunct treatment for triple-negative breast cancers. An introductory study. J Pharm Pharm Sci. 2014;17 (3) :439-46.|[2]Christina Nelson, et al. Therapeutic Efficacy of Esomeprazole in Cotton Smoke-Induced Lung Injury Model. Front Pharmacol. 2017 Jan 26;8:16.|[3]Thomas J Johnson, et al. Esomeprazole: a clinical review. Am J Health Syst Pharm. 2002 Jul 15;59 (14) :1333-9.