W-13 (hydrochloride)
Product Specifications
UNSPSC Description
W-13 hydrochloride is a calmodulin antagonist. W-13 hydrochloride can inhibit Tamoxifen (HY-13757A)-resistant human breast cancer cell growth[1].
Target Antigen
CaMK
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/w-13-hydrochloride.html
Purity
99.86
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=S(C1=CC=C2C(Cl)=CC=CC2=C1)(NCCCCN)=O.[H]Cl
Molecular Weight
349.28
References & Citations
[1]Tallant EA, et, al. Calmodulin antagonists elevate the levels of 32P-labeled polyphosphoinositides in human platelets. Biochem Biophys Res Commun. 1985 Aug 30;131(1):370-7.|[2]Strobl JS, et, al. Tamoxifen-resistant human breast cancer cell growth: inhibition by thioridazine, pimozide and the calmodulin antagonist, W-13. J Pharmacol Exp Ther. 1992 Oct;263(1):186-93.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-100910/W-13-hydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-100910/W-13-hydrochloride-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
88519-57-7
Available Sizes
Curated Selection
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