Raf inhibitor 2

Raf inhibitor 2 is a potent raf kinase (IC50[1].

Product Specifications

CAS Number

[220904-99-4]

UNSPSC

12352005

Hazard Statement

H302-H317

Target

Raf

Type

Reference compound

Related Pathways

MAPK/ERK Pathway

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/raf-kinase-in-1.html

Purity

98.48

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1NC2=C(C=C(Cl)C=C2)/C1=C/C3=CC(Br)=C(O)C(Br)=C3

Molecular Formula

C15H8Br2ClNO2

Molecular Weight

429.49

Precautions

P261-P264-P270-P272-P280-P302+P352-P330-P362+P364-P501

References & Citations

[1]German, et al. Benzylidene-1,3-dihydro-indol-2-one derivatives as receptor tyrosine kinase inhibitors, particularly of raf kinases. patent/EP1003721B1

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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