SIRT1 activator 2
SIRT1 activator 2 (compound 212) is a SIRT1 activator with an ED50 of [1].
Product Specifications
CAS Number
[863589-52-0]
UNSPSC
12352005
Hazard Statement
H315, H319
Target
Sirtuin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Metabolic Disease; Inflammation/Immunology; Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/sirtuin-modulator-7.html
Purity
99.28
Solubility
DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=CC(OC)=CC=C1)NC2=CC=CC(C3=NC4=CC=CN=C4S3)=C2
Molecular Formula
C20H15N3O2S
Molecular Weight
361.42
Precautions
H315, H319
References & Citations
[1]Nunes, et al. Preparation of benzimidazole derivatives as sirtuin modulators. WO2007019416. 2007-02-15
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
SIRT1
Available Sizes
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