Purified Anti-Human CD62L/SELL Antibody[DREG.55]

This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene.

Leukocyte adhesion molecule; Leukocyte surface antigen Leu; Leukocyte-endothelial cell adhesion molecule; LECAM; LAM; LEU; SELL; CD62L; LAM1; LECAM1; LEU8; LNHR; LSEL; LYAM1; PLNHR; TQ1; CD62 antigen-like family member L; CD62antigen-likefamilymemberL; gp90-MEL; LAM-1; Leu-8; Leukocyte adhesion molecule 1; Leukocyte surface antigen Leu-8; Leukocyte-endothelial cell adhesion molecule 1; L-selectin; Ly22; Ly-22; Lyam-1; Lymph node homing receptor; Lymphnodehomingreceptor;6&apos- sulfated Lewis X-X; LECAM-1; LAM-1