Pipazethate

Pipazethate (SKF 70230A), a pyridobenzothiazine derivative, is a potent GABA antagonist. Pipazethate has antitussive activity. Pipazethate can be used in research in cough supressant[1].

Product Specifications

CAS Number

[2167-85-3]

Product Name Alternative

SKF 70230A; SQ 15874; Pipazetate

UNSPSC

12352005

Target

GABA Receptor

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/pipazethate.html

Purity

99.0

Solubility

H2O : 1 mg/mL (ultrasonic; warming)

Smiles

O=C(N1C2=NC=CC=C2SC3=CC=CC=C13)OCCOCCN4CCCCC4

Molecular Formula

C21H25N3O3S

Molecular Weight

399.51

References & Citations

[1]Squires RF, et, al. Antidepressants and metabolites that block GABAA receptors coupled to 35S-t-butylbicyclophosphorothionate binding sites in rat brain. Brain Res. 1988 Feb 16;441 (1-2) :15-22.