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ABT-518

Product Specifications

UNSPSC Description

ABT-518 is a matrix metalloproteinase inhibitor with anti-tumor activity. ABT-518 has potent inhibitory effects on gelatinase A and gelatinase B, which can inhibit tumor growth and metastasis[1].

Target Antigen

MMP

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/abt-518.html

Smiles

O=CN([C@@H]([C@@H]1OC(C)(C)OC1)CS(=O)(C2=CC=C(OC3=CC=C(OC(F)(F)F)C=C3)C=C2)=O)O

Molecular Weight

505.46

References & Citations

[1]Chang S J, et al. The development of a large-scale synthesis of matrix metalloproteinase inhibitor, ABT-518[J]. Organic process research & development, 2002, 6(3): 329-335.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-13546/ABT-518-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-13546/

Clinical Information

Phase 1

CAS Number

286845-00-9

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