ABT-518
ABT-518 is a matrix metalloproteinase inhibitor with anti-tumor activity. ABT-518 has potent inhibitory effects on gelatinase A and gelatinase B, which can inhibit tumor growth and metastasis[1].
Product Specifications
CAS Number
[286845-00-9]
UNSPSC
12352005
Target
MMP
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/abt-518.html
Smiles
O=CN([C@@H]([C@@H]1OC(C)(C)OC1)CS(=O)(C2=CC=C(OC3=CC=C(OC(F)(F)F)C=C3)C=C2)=O)O
Molecular Formula
C21H22F3NO8S
Molecular Weight
505.46
References & Citations
[1]Chang S J, et al. The development of a large-scale synthesis of matrix metalloproteinase inhibitor, ABT-518[J]. Organic process research & development, 2002, 6 (3) : 329-335.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Curated Selection
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