Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Carbimazole (Standard)

Carbimazole (Standard) is the analytical standard of Carbimazole. This product is intended for research and analytical applications. Carbimazole is an orally active antithyroid agent which rapidly converts to Methimazole after absorption and prevents thyroid peroxidase enzyme from iodinating and coupling the tyrosine residues on thyroglobulin, hence reducing the production of thyroxine. Carbimazole also displays anti-inflammatory and neuronal-protective activities, suggesting its application for hyperthyroidism and neurological research[1][2][3].

Product Specifications

CAS Number

22232-54-8

UNSPSC

12352005

Target

P38 MAPK; Reference Standards

Type

Reference Standards

Related Pathways

MAPK/ERK Pathway; Others

Field of Research

Endocrinology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/carbimazole-standard.html

Smiles

O=C(N1C=CN(C)C1=S)OCC

Molecular Formula

C7H10N2O2S

Molecular Weight

186.23

References & Citations

[1]Nakashima, T. and A. Taurog, Rapid conversion of carbimazole to methimazole in serum; evidence for an enzymatic mechanism. Clin Endocrinol (Oxf), 1979. 10 (6) : p. 637-48.|[2]Lehane C, et al. Carbimazole is an inhibitor of protein synthesis and protects from neuronal hypoxic damage in vitro. J Pharmacol Exp Ther. 2013 Dec;347 (3) :781-93.|[3]H. Saeed, et al. Effects of Dose Level of Anti-thyroid Drug Carbimazole on Thermoregulation and Blood Constituents in Male Rabbits (Oryctolagus cuniculus) . Advances in Research, 2014, 2 (3), 129–144.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Clinical Information

Launched

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Phenazocine
TRC-P295400-5MG 5 mg

Phenazocine

Sign In for Pricing
View Details
LRRTM2 (NM_015564) Human Recombinant Protein
TP720484 10 µg

LRRTM2 (NM_015564) Human Recombinant Protein

Sign In for Pricing
View Details
P53 (Ab-382) Antibody
8D0037-AAT 50 µg

P53 (Ab-382) Antibody

Sign In for Pricing
View Details
Progesterone Receptor (PGR) Rabbit Monoclonal Antibody [Clone ID: R08-5E7]
TA421541 100 µL

Progesterone Receptor (PGR) Rabbit Monoclonal Antibody [Clone ID: R08-5E7]

Sign In for Pricing
View Details
Tissue FFPE Sections, Lung
CS703512 5x 5 µm

Tissue FFPE Sections, Lung

Sign In for Pricing
View Details
Frozen Tissue Sections, Lung
CS625308 5x 5 µm

Frozen Tissue Sections, Lung

Sign In for Pricing
View Details