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DGKζ-IN-4

DGKζ-IN-4 is a DGK-zeta inhibitor. DGKζ-IN-4 can be used as an active component of pharmaceutical compositions. DGKζ-IN-4 is used to treat cancers associated with immune cell activation or cancers resistant to anti-PD-1 antibody/anti-PD-11 antibody treatment[1].

Product Specifications

CAS Number

2778366-77-9

UNSPSC

12352005

Target

DGK

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/dgkζ-in-4.html

Purity

99.52

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

FC(F)(C1=C(N2C[C@H](N(CC2)C(OC(C)(C)C)=O)CO)C([N+]([O-])=O)=CC=C1OC3=C(C=CC=C3)Cl)F

Molecular Formula

C23H25ClF3N3O6

Molecular Weight

531.91

References & Citations

[1]Tu-Sekine B, et al. DGK-θ: Structure, Enzymology, and Physiological Roles. Front Cell Dev Biol. 2016 Sep 14;4:101.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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