Daidzin

Daidzin is an isoflavone with antioxidant, anticancer, and antiatherosclerotic activities. Daidzin is a potent and selective inhibitor of mitochondrial ALDH-2. Daidzin reduces ethanol consumption[1].

Product Specifications

CAS Number

[552-66-9]

Product Name Alternative

Daidzoside; NPI-031D; Daidzein 7-O-glucoside

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Aldehyde Dehydrogenase (ALDH) ; Mitochondrial Metabolism; Reverse Transcriptase

Type

Natural Products

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Field of Research

Others; Cardiovascular Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/Daidzin.html

Purity

99.77

Solubility

DMSO : ≥ 200 mg/mL

Smiles

OC1=CC=C(C2=COC(C=C(O[C@H]3[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O3)C=C4)=C4C2=O)C=C1

Molecular Formula

C21H20O9

Molecular Weight

416.38

Precautions

H302, H315, H319, H335

References & Citations

[1]Xie CI, et al. Daidzin, an antioxidant isoflavonoid, decreases blood alcohol levels and shortens sleep time induced by ethanol intoxication. Alcohol Clin Exp Res. 1994 Dec;18 (6) :1443-7.|[2]Keung WM, et al. Kudzu root: an ancient Chinese source of modern antidipsotropic agents. Phytochemistry. 1998 Feb;47 (4) :499-506.|[3]Keung WM, et al. Daidzin inhibits mitochondrial aldehyde dehydrogenase and suppresses ethanol intake of Syrian golden hamsters. Proc Natl Acad Sci U S A. 1997 Mar 4;94 (5) :1675-9.|[4]Keung WM, Vallee BL. Daidzin and its antidipsotropic analogs inhibit serotonin and dopamine metabolism in isolated mitochondria. Proc Natl Acad Sci U S A. 1998 Mar 3;95 (5) :2198-203.