GIP (1-30) amide, human
GIP (1-30) amide, human is a glucose-dependent insulinotropic polypeptide (GIP) fragment. GIP is an incretin hormone that stimulates insulin secretion and reduces postprandial glycaemic excursions. GIP (1-30) amide, human dose-dependently promotes insulin secretion over the range 10-9-10-6 M[1].
Product Specifications
CAS Number
198624-01-0
UNSPSC
12352209
Target
Insulin Receptor
Type
Peptides
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/gip-1-30-amide-human.html
Solubility
10 mM in DMSO
Smiles
NCCCC[C@@H](C(N)=O)NC([C@H](CCC(N)=O)NC([C@H](C)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@@H](NC([C@H](CC(N)=O)NC([C@H](C(C)C)NC([C@@H](NC([C@H](CC(O)=O)NC([C@H](CCC(N)=O)NC([C@H](CCC(N)=O)NC([C@@H](NC([C@H]([C@@H](C)CC)NC([C@H](CCCCN)NC([C@H](CC(O)=O)NC([C@H](CCSC)NC([C@H](C)NC([C@H]([C@@H](C)CC)NC([C@H](CO)NC([C@@H](NC([C@H](CC(O)=O)NC([C@H](CO)NC([C@H]([C@@H](C)CC)NC([C@@H](NC([C@H]([C@H](O)C)NC(CNC([C@H](CCC(O)=O)NC([C@H](C)NC([C@@H](N)CC1=CC=C(C=C1)O)=O)=O)=O)=O)=O)CC2=CC=CC=C2)=O)=O)=O)=O)CC3=CC=C(C=C3)O)=O)=O)=O)=O)=O)=O)=O)=O)CC4=CN=CN4)=O)=O)=O)=O)CC5=CC=CC=C5)=O)=O)=O)CC6=CNC7=CC=CC=C67)=O)=O)=O)=O)=O
Molecular Formula
C162H240N40O47S
Molecular Weight
3531.94
References & Citations
[1]Alaña I, et al. NMR structure of the glucose-dependent insulinotropic polypeptide fragment, GIP (1-30) amide. Biochem Biophys Res Commun. 2004 Dec 3;325 (1) :281-6.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
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