EAPB 02303
Product Specifications
UNSPSC Description
EAPB 02303 is a microtubule-disrupting agent and inhibitor. EAPB 02303 induces mitosis arrest and impairment of spindle assembly. Thus, EAPB 02303 induces apoptosis and exhibits antitumor activity. EAPB 02303 also exhibits a potent synergy with Paclitaxel (HY-B0015) at lower concentrations[1].
Target Antigen
Apoptosis; Microtubule/Tubulin
Type
Reference compound
Related Pathways
Apoptosis;Cell Cycle/DNA Damage;Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/eapb-02303.html
Solubility
H2O : 30 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
OC(C=C1)=C(O)C=C1C2=CN=C3C(NC)=NC4=CC=CC=C4N32
Molecular Weight
306.32
References & Citations
[1]Bigot K, et al. Imiqualines for pancreatic cancer: first-in-class potent and synergistic inhibitors of microtubule polymerisation[J]. Cancer Research, 2023, 83(7_Supplement): 5729-5729.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-153384/EAPB-02303-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-153384/EAPB-02303-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1958290-51-1
Available Sizes
Curated Selection
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