SpCas9 D10A Nickase
SpCas9 D10A Nickase is a mutant of the Cas9 protein. SpCas9 D10A Nickase retains the function of a cleavage domain of Cas9 nuclease and specifically cleaves the target single strand to form a nick. SpCas9 D10A Nickase reduces off-target effects[1].
Product Specifications
UNSPSC
12352204
Target
Biochemical Assay Reagents; CRISPR/Cas9
Type
Enzyme
Related Pathways
Cell Cycle/DNA Damage; Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/spcas9-d10a-nickase.html
Solubility
10 mM in DMSO
Smiles
[SpCas9D10ANickase]
References & Citations
[1]Jasper Che-Yung Chien, et al. Multiplexed bioluminescence-mediated tracking of DNA double-strand break repairs in vitro and in vivo. Nat Protoc. 2021, 16, 8.
Shipping Conditions
Room temperature
Scientific Category
Enzyme
Clinical Information
No Development Reported
Curated Selection
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