Hepcidin-1 (mouse)
Hepcidin-1 (mouse) is an endogenous peptide hormone involved in the regulation of iron homeostasis. Hepcidin-1 (mouse) upregulates mRNA levels of TRAP, cathepsin K, and MMP-9 and increases TRAP-5b protein secretion. Hepcidin-1 (mouse) downregulates the level of FPN1 protein and increases intracellular iron. Hepcidin-1 (mouse) facilitates osteoclast differentiation[1].
Product Specifications
CAS Number
1676104-75-8
UNSPSC
12352209
Target
Cathepsin; Hepcidin; MMP
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/hepcidin-1-mouse.html
Solubility
10 mM in DMSO
Smiles
OC(C[C@H](N)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(N)=O)C(N[C@@H](CC1=CC=CC=C1)C(N2[C@@H](CCC2)C(N[C@@H]([C@@H](C)CC)C(N[C@@H]3C(N[C@@](C(N[C@H](C(N[C@]4([H])C(N[C@]5([H])C(N[C@H](C(N[C@]6([H])C(N[C@](CSSC6)([H])C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@](C(NCC(N[C@@](C(N[C@](CSSC4)([H])C(N[C@@H](CSSC3)C(N[C@@H](CCCCN)C(N[C@H](C(O)=O)[C@H](O)C)=O)=O)=O)=O)([H])[C@@H](C)CC)=O)=O)([H])CSSC5)=O)CCC(N)=O)=O)CO)=O)CC(N)=O)=O)CC(N)=O)=O)=O)=O)CCCCN)=O)=O)=O)CC7=CC=CC=C7)=O)([H])[C@@H](C)CC)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C111H169N31O35S8
Molecular Weight
2754.24
References & Citations
[1]Zhao GY, et al. Effects of mouse hepcidin 1 treatment on osteoclast differentiation and intracellular iron concentration. Inflammation. 2015 Apr;38 (2) :718-27.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
Cathepsin K; MMP-9
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