Hypusine

Hypusine is a natural amino acid. The post-translational synthesis of hypusine is mainly catalyzed by deoxyhypusine synthase (DHPS) and deoxyhypusine hydroxylase (DOHH) [1][2].

Product Specifications

CAS Number

[34994-11-1]

UNSPSC

12352211

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/hypusine.html

Smiles

N[C@H](C(O)=O)CCCCNC[C@@H](CCN)O

Molecular Formula

C10H23N3O3

Molecular Weight

233.31

References & Citations

[1]Shiba T, et al. Hypusine, a new amino acid occurring in bovine brain. Isolation and structural determination. Biochim Biophys Acta. 1971 Sep 21;244 (3) :523-31. |[2]ark MH, et al. Hypusine, a polyamine-derived amino acid critical for eukaryotic translation. J Biol Chem. 2018 Nov 30;293 (48) :18710-18718.