Hypusine
Hypusine is a natural amino acid. The post-translational synthesis of hypusine is mainly catalyzed by deoxyhypusine synthase (DHPS) and deoxyhypusine hydroxylase (DOHH) [1][2].
Product Specifications
CAS Number
34994-11-1
UNSPSC
12352211
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/hypusine.html
Smiles
N[C@H](C(O)=O)CCCCNC[C@@H](CCN)O
Molecular Formula
C10H23N3O3
Molecular Weight
233.31
References & Citations
[1]Shiba T, et al. Hypusine, a new amino acid occurring in bovine brain. Isolation and structural determination. Biochim Biophys Acta. 1971 Sep 21;244 (3) :523-31. |[2]ark MH, et al. Hypusine, a polyamine-derived amino acid critical for eukaryotic translation. J Biol Chem. 2018 Nov 30;293 (48) :18710-18718.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite
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