Hydroxystilbamidine

Hydroxystilbamidine, a dye capable of binding to both DNA and RNA, is a powerful inhibitor of cellular ribonucleases. Hydroxystilbamidine is a retrograde fluorescent tracer and a histochemical stain[1][2].

Product Specifications

CAS Number

[495-99-8]

UNSPSC

12171500

Hazard Statement

H302-H312-H332

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/hydroxystilbamidine.html

Solubility

10 mM in DMSO

Smiles

NC(C1=CC=C(/C=C/C2=C(O)C=C(C(N)=N)C=C2)C=C1)=N

Molecular Formula

C16H16N4O

Molecular Weight

280.32

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

References & Citations

[1]Folds JD, et al. Immunosuppression by hydroxystilbamidine isethionate, a lysosome-stabilizing, anti-proteolytic, antifungal drug. Infect Immun. 1975 Mar;11 (3) :441-4.|[2]Festy B, et al. Hydroxystilbamidine. A nonintercalating drug as a probe of nucleic acid conformation. Biochemistry. 1973 Nov 20;12 (24) :4827-34.