Bicalutamide
Bicalutamide is an orally active non-steroidal androgen receptor (AR) antagonist. Bicalutamide can be used for the research of prostate cancer[1].
Product Specifications
CAS Number
[90357-06-5]
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Androgen Receptor; Autophagy
Type
Reference compound
Related Pathways
Autophagy; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Bicalutamide.html
Concentration
10mM
Purity
99.92
Solubility
DMSO : ≥ 50 mg/mL
Smiles
FC1=CC=C(S(=O)(CC(O)(C(NC2=CC=C(C#N)C(C(F)(F)F)=C2)=O)C)=O)C=C1
Molecular Formula
C18H14F4N2O4S
Molecular Weight
430.37
Precautions
H315, H319, H335
References & Citations
[1]Nicola J. Clegg,1 John Wongvipat,1,2 Jim Joseph, ARN-509: a novel anti-androgen for prostate cancer treatment. Cancer Res. 2012 March 15; 72 (6) : 1494-1503.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
Curated Selection
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