Tacrolimus 8-epimer
Tacrolimus anhydrous 8-epimer (Tacrolimus EP impurity D) is a l-pipecolic acid macrolide lactone, an important immunosuppressive agent that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2[1].
Product Specifications
CAS Number
[129212-35-7]
Product Name Alternative
Tacrolimus EP impurity D; 8-epi-Tacrolimus
UNSPSC
12352005
Hazard Statement
H301
Target
Phosphatase
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Purity
96.64
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CO[C@@H]1[C@]2([H])O[C@]([C@@H](C1)C)(C(C(N3[C@](CCCC3)([H])C(O[C@@H]([C@@H]([C@H](CC([C@H](/C=C(C[C@@H](C[C@@H]2OC)C)\C)CC=C)=O)O)C)/C(C)=C/[C@H]4C[C@H]([C@@H](CC4)O)OC)=O)=O)=O)O
Molecular Formula
C44H69NO12
Molecular Weight
804.02
Precautions
H301
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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