Dihydromevinolin
Dihydromevinolin is a potent hypocholesterolemic metabolite produced by Aspergillus terreus. Dihydromevinolin is a HMG-CoA reductase inhibitor[1].
Product Specifications
CAS Number
77517-29-4
Product Name Alternative
Lovastatin EP impurity E; 4a,5-Dihydromevinolin
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Endogenous Metabolite; HMG-CoA Reductase (HMGCR)
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Smiles
CC[C@H](C)C(O[C@@H]1[C@@]2([H])[C@@](C[C@@H](C1)C)([H])C=C[C@@H]([C@@H]2CC[C@@H]3C[C@H](CC(O3)=O)O)C)=O
Molecular Formula
C24H38O5
Molecular Weight
406.56
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]G Albers-Schönberg, et al. Dihydromevinolin, a potent hypocholesterolemic metabolite produced by Aspergillus terreus. J Antibiot (Tokyo) . 1981 May;34 (5) :507-12.|[2]G Albers-Schönberg, et al. Dihydromevinolin, a potent hypocholesterolemic metabolite produced by Aspergillus terreus. J Antibiot (Tokyo) . 1981 May;34 (5) :507-12.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Microbial Metabolite
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