Dihydromevinolin

Dihydromevinolin is a potent hypocholesterolemic metabolite produced by Aspergillus terreus. Dihydromevinolin is a HMG-CoA reductase inhibitor[1].

Product Specifications

CAS Number

[77517-29-4]

Product Name Alternative

Lovastatin EP impurity E; 4a,5-Dihydromevinolin

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Endogenous Metabolite; HMG-CoA Reductase (HMGCR)

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease

Smiles

CC[C@H](C)C(O[C@@H]1[C@@]2([H])[C@@](C[C@@H](C1)C)([H])C=C[C@@H]([C@@H]2CC[C@@H]3C[C@H](CC(O3)=O)O)C)=O

Molecular Formula

C24H38O5

Molecular Weight

406.56

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]G Albers-Schönberg, et al. Dihydromevinolin, a potent hypocholesterolemic metabolite produced by Aspergillus terreus. J Antibiot (Tokyo) . 1981 May;34 (5) :507-12.|[2]G Albers-Schönberg, et al. Dihydromevinolin, a potent hypocholesterolemic metabolite produced by Aspergillus terreus. J Antibiot (Tokyo) . 1981 May;34 (5) :507-12.