(Z) -Flunarizine
(Z) -Flunarizine is the (Z) -isomer of Flunarizine. Flunarizine is a potent dual Na+/Ca2+ channel (T-type) blocker. Flunarizine is a D2 dopamine receptor antagonist. Flunarizine shows anticonvulsive and antimigraine activity, and peripheral vasodilator effects[1].
Product Specifications
CAS Number
693765-11-6
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Sodium Channel
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Neurological Disease
Smiles
FC(C=C1)=CC=C1C(C2=CC=C(C=C2)F)N3CCN(CC3)C/C=C\C4=CC=CC=C4
Molecular Formula
C26H26F2N2
Molecular Weight
404.49
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Shakhmaev, R. N.; Sunagatullina, A. Sh.; Zorin, V. V. Fe-catalyzed synthesis of flunarizine and its (Z) -isomer. Russian Journal of General Chemistry (2016), 86 (8), 1969-1972
Shipping Conditions
Room temperature
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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