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(Z) -Flunarizine

(Z) -Flunarizine is the (Z) -isomer of Flunarizine. Flunarizine is a potent dual Na+/Ca2+ channel (T-type) blocker. Flunarizine is a D2 dopamine receptor antagonist. Flunarizine shows anticonvulsive and antimigraine activity, and peripheral vasodilator effects[1].

Product Specifications

CAS Number

693765-11-6

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Sodium Channel

Related Pathways

Membrane Transporter/Ion Channel

Field of Research

Neurological Disease

Smiles

FC(C=C1)=CC=C1C(C2=CC=C(C=C2)F)N3CCN(CC3)C/C=C\C4=CC=CC=C4

Molecular Formula

C26H26F2N2

Molecular Weight

404.49

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Shakhmaev, R. N.; Sunagatullina, A. Sh.; Zorin, V. V. Fe-catalyzed synthesis of flunarizine and its (Z) -isomer. Russian Journal of General Chemistry (2016), 86 (8), 1969-1972

Shipping Conditions

Room temperature

Scientific Category

Reference compound2

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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