N-Desmethyl diltiazem (hydrochloride)
N-Desmethyl diltiazem hydrochloride is a substrate for CYP3A7 metabolism, which is the predominant fetal form and is minimally expressed in adults[1].
Product Specifications
CAS Number
[130606-60-9]
UNSPSC
12352005
Hazard Statement
H302
Target
Cytochrome P450
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Purity
90.0
Smiles
[H]Cl.CC(O[C@@H]1[C@H](C2=CC=C(C=C2)OC)SC3=CC=CC=C3N(C1=O)CCNC)=O
Molecular Formula
C21H25ClN2O4S
Molecular Weight
436.95
Precautions
H302
References & Citations
[1]Williams JA, et al. Comparative metabolic capabilities of CYP3A4, CYP3A5, and CYP3A7. Drug Metab Dispos. 2002 Aug;30 (8) :883-91.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CYP3
Available Sizes
Curated Selection
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