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(R) - (+) -Bupivacaine (hydrochloride)

(R) - (+) -Bupivacaine hydrochloride is a voltage-gated sodium channel inhibitor. (R) - (+) -Bupivacaine hydrochloride can selectively block the voltage-gated sodium channels on nerve cell membranes, inhibit the influx of sodium ions, and thus prevent the generation and conduction of nerve impulses, exerting local anesthetic activity. (R) - (+) -Bupivacaine hydrochloride can be used in research of acute pains[1].

Product Specifications

CAS Number

27262-46-0

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Sodium Channel

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Smiles

CC(C=CC=C1C)=C1NC([C@@H]2N(CCCC2)CCCC)=O.Cl

Molecular Formula

C18H29ClN2O

Molecular Weight

324.89

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Schmidt AC. The role of molecular structure in the crystal polymorphism of local anesthetic drugs: crystal polymorphism of local anesthetic drugs, part X. Pharm Res. 2005 Dec;22 (12) :2121-33.

Shipping Conditions

Room temperature

Scientific Category

Reference compound2

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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