Etoricoxib N1'-oxide
Etoricoxib N1'-oxide is an Etoricoxib (HY-15321) metabolite. Etoricoxib N1'-oxide does not inhibit COX-1, nor does it significantly inhibit COX-2[1].
Product Specifications
CAS Number
[325855-74-1]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Drug Metabolite
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Purity
99.97
Smiles
O=S(C1=CC=C(C2=CC(Cl)=CN=C2C3=C[N+]([O-])=C(C)C=C3)C=C1)(C)=O
Molecular Formula
C18H15ClN2O3S
Molecular Weight
374.84
Precautions
H302, H315, H319, H335
References & Citations
[1]Chauret N, et, al. In vitro metabolism considerations, including activity testing of metabolites, in the discovery and selection of the COX-2 inhibitor etoricoxib (MK-0663) . Bioorg Med Chem Lett. 2001 Apr 23;11 (8) :1059-62.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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