(R) -Esomeprazole

(R) -Esomeprazole ((R) -Omeprazole; (+) -Omeprazole) is an orally active cytochrome P450 2C19, CYP3A4, and CYP2C9-related metabolic modulator. (R) -Esomeprazole can be used in studies of digestive system diseases and compound metabolic interactions[1][2].

Product Specifications

CAS Number

[119141-89-8]

Product Name Alternative

(R) -Omeprazole; (+) -Omeprazole

UNSPSC

12352005

Hazard Statement

H315-H319-H335

Target

Cytochrome P450

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Inflammation/Immunology; Metabolic Disease

Smiles

O=[S@@](C1=NC2=CC(OC)=CC=C2N1)CC3=NC=C(C)C(OC)=C3C

Molecular Formula

C17H19N3O3S

Molecular Weight

345.42

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

References & Citations

[1]Pippa LF, et al. Impact of obesity and roux-en-Y gastric bypass on the pharmacokinetics of (R) - and (S) -omeprazole and intragastric pH. CPT Pharmacometrics Syst Pharmacol. 2024 Sep;13 (9) :1528-1541. |[2]Niwa T, et al. Stereoselectivity of human cytochrome p450 in metabolic and inhibitory activities. Curr Drug Metab. 2011 Jul;12 (6) :549-69.