DPP-4-IN-18
DPP-4-IN-18 (Sitagliptin impurity 3) (Compound 4) impurity 3 is a potent, selective and orally active DPP-4 inhibitor with an IC50 of 27 nM. DPP-4-IN-18 can effectively prevent DPP-4 from degrading glucagon-like peptide 1 (GLP-1), thereby increasing the level of active GLP-1. DPP-4-IN-18 can be used for the research of type 2 diabetes[1].
Product Specifications
Product Name Alternative
Sitagliptin impurity 3
UNSPSC
12352005
Hazard Statement
H319-H373
Target
Dipeptidyl Peptidase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Smiles
O=C(N1CC2=NN=C(C(F)(F)F)N2CC1)C[C@H](N)CC3=CC(F)=CC=C3F
Molecular Formula
C16H16F5N5O
Molecular Weight
389.32
Precautions
P260-P264-P280-P305+P351+P338-P501
References & Citations
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-Z1764/
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Isoform
DPP-4
CAS Number
[486460-31-5]
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