Caffeoylmalic acid

Caffeoylmalic acid is an orally active hydroxycinnamoyl-malate ester found in stinging nettle (Urtica dioica) . Caffeoylmalic acid exhibits anti-diabetic, anti-inflammation and anti-oxidant effects. Caffeoylmalic acid shows cytotoxicity to cancer cells. Caffeoylmalic acid can be used for the researches of cancer, inflammation and metabolic disease, such as colon cancer and diabetes[1][2][3].

Product Specifications

CAS Number

[39015-77-5]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Others

Related Pathways

Others

Field of Research

Cancer; Metabolic Disease; Inflammation/Immunology

Smiles

O=C(/C=C/C1=CC=C(C(O)=C1)O)OC(CC(O)=O)C(O)=O

Molecular Formula

C13H12O8

Molecular Weight

296.23

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Rehman G, et al. Antidiabetic Properties of Caffeoylmalic Acid, a Bioactive Natural Compound Isolated from Urtica dioica. Fitoterapia. 2024 Jul;176:106024. |[2]Delgadillo Puga C, et al. Phenolic Compounds in Organic and Aqueous Extracts from Acacia farnesiana Pods Analyzed by ULPS-ESI-Q-oa/TOF-MS. In Vitro Antioxidant Activity and Anti-Inflammatory Response in CD-1 Mice. Molecules. 2018 Sep 18;23 (9) :2386.|[3]Wójciak M, et al. Antioxidant and Anti-Inflammatory Effects of Nettle Polyphenolic Extract: Impact on Human Colon Cells and Cytotoxicity Against Colorectal Adenocarcinoma. Molecules. 2024 Oct 22;29 (21) :5000.