Silodosin carboxylic acid impurity

Silodosin carboxylic acid impurity (KMD-3293) is an inactive silodosin metabolite. Silodosin carboxylic acid impurity is the major metabolite that can be generated via oxidation by alcohol and aldehyde dehydrogenase. Silodosin carboxylic acid impurity can be studied in research for benign prostatic hyperplasia[1][2].

Product Specifications

CAS Number

[1357252-79-9]

Product Name Alternative

KMD-3293

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Endogenous Metabolite

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease

Smiles

OC(CCN1C2=C(C(N)=O)C=C(C[C@@H](C)NCCOC3=C(C=CC=C3)OCC(F)(F)F)C=C2CC1)=O

Molecular Formula

C25H30F3N3O5

Molecular Weight

509.52

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Shah, P. A., & Shrivastav, P. S. (2018) . Novel LC-MS/MS method for the quantification of silodosin and its metabolites in human plasma. Bioanalysis, 10 (1), 7–10.|[2]Lepor, H., & Hill, L. A. (2010) . Silodosin for the treatment of benign prostatic hyperplasia: pharmacology and cardiovascular tolerability. Pharmacotherapy, 30 (12), 1303–1312.