HOAT

HOAT is a commonly used peptide bond forming agent that may become an impurity in drug synthesis, but is not mutagenic. HOAT can be used for peptide fragment polycondensation and can also inhibit the racemization of peptide polycondensation[1].

Product Specifications

CAS Number

[39968-33-7]

UNSPSC

12352005

Hazard Statement

H228, H315, H319

Target

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Others

Purity

99.99

Solubility

DMSO : 200 mg/mL (ultrasonic)

Smiles

ON1C2=NC=CC=C2N=N1

Molecular Formula

C5H4N4O

Molecular Weight

136.11

Precautions

H228, H315, H319

References & Citations

[1]Nicolette J, et al. Peptide bond-forming reagents HOAt and HATU are not mutagenic in the bacterial reverse mutation test. Environ Mol Mutagen. 2016 Apr;57 (3) :236-40.